Domain Associates, LLC

Portfolio Companies (By Industry)

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		3F Therapeutics, Inc. Devices to treat heart valve disorders Acquired by ATS Medical, Inc.

		Achaogen, Inc. Pursuing unique strategies to prevent drug resistance

		Acureon Pharmaceuticals, Inc. Acquire and market drugs focused on infectious diseases, transplant and ICU.

		Aesthetic Sciences Corporation Focused on aesthetic medicine and incontinence
Aesthetic Sciences Corporation

		Align Technology, Inc. Invisalign® invisible braces

		Alimera Sciences, Inc. Development and marketing of in-licensed ophthalmology products

		Altea Therapeutics Corporation Delivery of drugs across the skin

		Amylin Pharmaceuticals, Inc. Development of drugs to treat metabolic diseases

		Ansata Therapeutics, Inc. Drug development utilizing cell targeting technology

		Apnex Medical, Inc. Developing a device-based treatment for obstructive sleep apnea

		Applied Molecular Evolution, Inc. Gene evolution technology to optimize proteins for drug and industrial use Acquired by Eli Lilly & Co.
Applied Molecular Evolution, Inc.

		Ascenta Therapeutics, Inc. Anti-cancer drug development

		Asmacure, Inc. Developing therapeutics for the treatment of asthma
Asmacure, Inc.

		Athena Neurosciences, Inc. Development of diagnostics and therapeutics for Alzheimer's Disease Acquired by Elan Corporation
Athena Neurosciences, Inc.

		AtheroGenics, Inc. Discovery and development of drugs for inflammatory diseases

		Aurora Biosciences Corporation Automation to facilitate drug discovery processes Acquired by Vertex Pharmaceuticals
Aurora Biosciences Corporation

		Auxeris Therapeutics, Inc. Osteoporosis drug development

		Biomagnetic Technologies Inc. Instrumentation for ultra-sensitive magnetic measurement
Biomagnetic Technologies Inc.

		Biosite Diagnostics, Inc. Discovery, development and marketing of rapid diagnostics

		BioVascular, Inc. Developing solutions for reducing inflammation and thrombosis

		BiPar Sciences, Inc. Developing and commercializing potential new classes of tumor-selective drugs

		British Biotech Diversified life-sciences company developing both drugs and research products Merged with Vernalis pls
British Biotech

		Cabrellis Pharmaceuticals Corporation Development of important therapies for the treatment of cancer Acquired by Pharmion Corporation

		Cadence Pharmaceuticals, Inc. Development and marketing of acute care drugs with an initial focus on anti-infectives

		Cadent Medical Corporation Life-saving external defibrillators Acquired by Cardiac Science, Inc.
Cadent Medical Corporation

		Calixa Therapeutics, Inc. Focused on developing, acquiring and commercializing hospital-based anti-infective therapies
Calixa Therapeutics, Inc.

		Cardiac Science Corporation Life-saving external defibrillators

		CardioDynamics International Corporation Noninvasive digital heart monitoring devices

		CareCentric Solutions, Inc. Information systems for the home care industry Acquired by Simione Central Holdings, renamed Care Centric

		Carticept Medical, Inc. Development and sales of therapeutically related medical devices

		Celator Pharmaceuticals, Inc. Development of proprietary fixed dose combinations of chemotherapeutic agents for cancer treatment

		Cell Biosciences, Inc. Lab instrumentation enabling analysis of cell signaling activity

		Celladon Corporation Developing treatments for cardiovascular diseases through molecular cardiology

		Cerexa, Inc. Focused on developing, acquiring and commercializing hospital-based anti-infective therapies Acquired by Forest Laboratories, Inc.

		Ciblex Corporation Development of drugs that impact protein trafficking for use in proliferative disorders

		CoCensys, Inc. Development of CNS drugs targeted at novel CNS receptors Acquired by Purdue Pharma
CoCensys, Inc.

		CoDa Therapeutics, Inc. Development and commercialization of wound care therapeutics based on gap junction modulation

		CoLucid Pharmaceuticals, Inc. Developing innovative therapies to treat CNS disorders

		Conforma Therapeutics Corporation Anti-cancer drug development Acquired by Biogen IDEC

		Connetics Corporation Development and marketing of dermatology drugs

		Corthera, Inc. Development of Relaxin for various indications

		Creative Biomolecules, Inc. Development of regenerative medicines Merged into Curis, Inc.
Creative Biomolecules, Inc.

		Cytovia, Inc. Drug screening technology using proprietary apoptosis assays Acquired by Maxim Pharmaceuticals, Inc.
Cytovia, Inc.

		DiObex, Inc. Development of drugs to improve the management of diabetic patients

		DNX Corporation Development of in vitro and in vivo biological models Merged with BioClin to form Chrysalis International Corporation, subsequently acquired by Phoenix International Life Sciences, now part of MDS Pharma
DNX Corporation

		Domain AntiBacterial Acquisition Corporation In-licensing of anti-infective drugs Acquired by Peninsula Pharmaceuticals, Inc.
Domain AntiBacterial Acquisition Corporation

		Dura Pharmaceuticals, Inc. Specialty pharmaceutical company focused on respiratory drugs Acquired by Elan Corporation
Dura Pharmaceuticals, Inc.

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